Novel photoactivated Indole-pyridine chemotherapeutics with strong antimicrobial and antibiofilm activity toward Staphylococcus aureus.

Zhang, Zhishang; Li, Wenqing; Wu, Haorui; Liu, Zhuangfeng; Huang, Huaiyi

Zhang, Zhishang; Li, Wenqing; Wu, Haorui; Liu, Zhuangfeng; Huang, Huaiyi.

Afiliación

Zhang Z; School of Pharmaceutical Science (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Li W; School of Pharmaceutical Science (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Wu H; School of Pharmaceutical Science (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Liu Z; Department of Process Research and Development, HEC Pharm Group, Dongguan 523871, China.
Huang H; School of Pharmaceutical Science (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. Electronic address: huanghy87@mail.sysu.edu.cn.

Bioorg Chem ; 140: 106813, 2023 11.

Article en En | MEDLINE | ID: mdl-37657196

Asunto(s)

Antiinfecciosos; Infecciones Estafilocócicas; Humanos; Staphylococcus aureus; NAD; Piridinas/farmacología; Biopelículas; Indoles/farmacología

Palabras clave

Antibacterial photodynamic therapy; NAD(P)H; Photocatalysis; Singlet oxygen; Superoxide anion

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Infecciones Estafilocócicas / Antiinfecciosos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2023 Tipo del documento: Article País de afiliación: China

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