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Evaluation of 3-dimensional stereotactic surface projection rendering of arterial spin labeling data in a clinical cohort.
Andre, Jalal B; Oztek, Murat Alp; Anzai, Yoshimi; Wilson, Gregory J; Mossa-Basha, Mahmud; Hippe, Daniel S; Hoff, Michael N; Cross, Donna J; Minoshima, Satoshi.
Afiliación
  • Andre JB; Department of Radiology, University of Washington, Seattle, Washington, USA.
  • Oztek MA; Department of Radiology, University of Washington, Seattle, Washington, USA.
  • Anzai Y; Department of Radiology, University of Utah, Salt Lake City, Utah, USA.
  • Wilson GJ; Department of Radiology, University of Washington, Seattle, Washington, USA.
  • Mossa-Basha M; Department of Radiology, University of Washington, Seattle, Washington, USA.
  • Hippe DS; Department of Radiology, University of Washington, Seattle, Washington, USA.
  • Hoff MN; Department of Radiology, University of Washington, Seattle, Washington, USA.
  • Cross DJ; Department of Radiology, University of Utah, Salt Lake City, Utah, USA.
  • Minoshima S; Department of Radiology, University of Utah, Salt Lake City, Utah, USA.
J Neuroimaging ; 33(6): 933-940, 2023.
Article en En | MEDLINE | ID: mdl-37695098
ABSTRACT
BACKGROUND AND

PURPOSE:

To assess the feasibility of 3-dimensional stereotactic surface projection (3D-SSP) as applied to arterial spin labeling (ASL) in a clinical pilot study.

METHODS:

A retrospective sample of 10 consecutive patients who underwent ASL as part of a clinically indicated MR examination was collected during this pilot study. Five additional subjects with normal cerebral perfusion served as a control group. Following voxel-wise M0-correction, cerebral blood flow (CBF) quantification, and stereotactic anatomic standardization, voxel-wise CBF from an individual's ASL dataset was extracted to a set of predefined surface pixels (3D-SSP). A normal database was created from averaging the extracted CBF datasets of the control group. Patients' datasets were compared individually with the normal database by calculating a Z-score on a pixel-by-pixel basis and were displayed in 3D-SSP views for visual inspection. Independent, two-expert reader assessment, using a 3-point scale, compared standard quantitative CBF images to the 3D-SSP maps.

RESULTS:

Patterns and severities of regionally reduced CBF were identified, by both independent readers, in the 3D-SSP maps. Reader assessment demonstrated preference for 3D-SSP over traditionally displayed standard quantitative CBF images in three of four evaluated imaging metrics (p = .026, .031, and .013, respectively); 3D-SSP maps were never found to be inferior to the standard quantitative CBF images.

CONCLUSIONS:

Three-dimensional SSP maps are feasible in a clinical population and enable quantitative data extraction and localization of perfusion abnormalities by means of stereotactic coordinates in a condensed display. The proposed method is a promising approach for interpreting cerebrovascular pathophysiology.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Arterias / Imagenología Tridimensional Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Neuroimaging Asunto de la revista: DIAGNOSTICO POR IMAGEM / NEUROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Arterias / Imagenología Tridimensional Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Neuroimaging Asunto de la revista: DIAGNOSTICO POR IMAGEM / NEUROLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos