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BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation and antitumor effects in preclinical models.
Jiang, Beibei; Zhang, Tong; Deng, Minjuan; Jin, Wei; Hong, Yuan; Chen, Xiaotong; Chen, Xin; Wang, Jing; Hou, Hongjia; Gao, Yajuan; Gong, Wenfeng; Wang, Xing; Li, Haiying; Zhou, Xiaosui; Feng, Yingcai; Zhang, Bo; Jiang, Bin; Lu, Xueping; Zhang, Lijie; Li, Yang; Song, Weiwei; Sun, Hanzi; Wang, Zuobai; Song, Xiaomin; Shen, Zhirong; Liu, Xuesong; Li, Kang; Wang, Lai; Liu, Ye.
Afiliación
  • Jiang B; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Zhang T; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Deng M; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Jin W; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Hong Y; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Chen X; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Chen X; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Wang J; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Hou H; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Gao Y; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Gong W; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Wang X; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Li H; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Zhou X; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Feng Y; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Zhang B; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Jiang B; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Lu X; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Zhang L; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Li Y; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Song W; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Sun H; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Wang Z; Department of Clinic Development, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Song X; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Shen Z; Department of Discovery Biomarkers, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Liu X; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Li K; Department of Biologics, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Wang L; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China.
  • Liu Y; Department of Biology, BeiGene (Beijing) Co., Ltd., Beijing, 102206, China. ye.liu@beigene.com.
Front Med ; 17(6): 1170-1185, 2023 Dec.
Article en En | MEDLINE | ID: mdl-37747585
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores del Factor de Necrosis Tumoral / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Med Año: 2023 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores del Factor de Necrosis Tumoral / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Med Año: 2023 Tipo del documento: Article País de afiliación: China