FBXW10: a male-biased E3 ligase in liver cancer.
Trends Cancer
; 9(11): 876-878, 2023 11.
Article
en En
| MEDLINE
| ID: mdl-37775405
ABSTRACT
Two recent studies, by Lin et al. and Liu et al., unveiled the pivotal role of F-box and WD repeat domain containing 10 (FBXW10)-mediated ubiquitination and activation of oncogenic signaling as the primary driver behind the higher prevalence of hepatocellular carcinoma (HCC) in men. These discoveries shed light on underlying mechanisms of sex-biased cancer and provide a promising roadmap for both basic and clinical research.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Carcinoma Hepatocelular
/
Proteínas F-Box
/
Neoplasias Hepáticas
Tipo de estudio:
Risk_factors_studies
Límite:
Humans
/
Male
Idioma:
En
Revista:
Trends Cancer
Año:
2023
Tipo del documento:
Article