Leflunomide alleviates obesity via activation of the TAK1-AMPK pathway and induction of lipophagy.

Ji, Xiaoyue; Chen, Junhong; You, Chaoying; Sun, Jing; Xu, Xiulong

Ji, Xiaoyue; Chen, Junhong; You, Chaoying; Sun, Jing; Xu, Xiulong.

Afiliación

Ji X; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Chen J; Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou, China.
You C; School of Animal Science and Food Engineering, Jinling Institute of Technology, Nanjing, China.
Sun J; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Xu X; Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.

FASEB J ; 37(11): e23227, 2023 11.

Article en En | MEDLINE | ID: mdl-37792678

Asunto(s)

Proteínas Quinasas Activadas por AMP; Autofagia; Ratones; Humanos; Animales; Leflunamida/farmacología; Proteínas Quinasas Activadas por AMP/metabolismo; Obesidad/tratamiento farmacológico

Palabras clave

A77 1726; autophagy; leflunomide; lipophagy; obesity; p70 S6 kinase 1

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Proteínas Quinasas Activadas por AMP Límite: Animals / Humans Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China

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