Functional rehabilitation based on therapeutic exercise training in patients with postacute COVID syndrome (RECOVER).
Rev Esp Cardiol (Engl Ed)
; 77(2): 167-175, 2024 Feb.
Article
en En, Es
| MEDLINE
| ID: mdl-37797937
ABSTRACT
INTRODUCTION AND OBJECTIVES:
Postacute COVID syndrome (PACS) is common after acute SARS-CoV-2 infection. One of the most frequent and disabling symptoms is exercise intolerance (EI). Recent evidence suggests that EI in PACS has a peripheral (metabolic-neuromuscular) origin, suggesting that exercise training may be an effective treatment. The aim of this study was to assess the role a therapeutic physical exercise program (TPEP) in PACS with EI.METHODS:
This single-center, open-label, randomized clinical trial compared an exercise training program (intervention group) with regular physical activity recommendations (control group) in patients with PACS and EI. The intervention group underwent an 8-week TPEP. The primary endpoint was improvement in functional capacity, assessed as the change in peak VO2.RESULTS:
We included 50 participants with PACS (73% women, mean age 47±7.1 years). The intervention group showed a 15% improvement in peak VO2 (peak VO2 pre- and postintervention 25.5±7.7mL/kg/min and 29.3±4.7 mL/kg/min; P <.001) and a 13.2% improvement in predicted values (92.1±14.3% and 108.4±13.4%; P <.001). No significant changes in VO2 values were observed in the control group. Unlike the control group, the intervention group also showed improvements in all secondaryoutcomes:
quality of life scales, muscle power, maximum inspiratory power, metabolic flexibility, and body fat percentage.CONCLUSIONS:
The program improved functional capacity in patients with PACS and EI.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Calidad de Vida
/
COVID-19
Tipo de estudio:
Clinical_trials
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Guideline
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Prognostic_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
/
Es
Revista:
Rev Esp Cardiol (Engl Ed)
Año:
2024
Tipo del documento:
Article