Microdosimetry of a 62-MeV clinical proton beam with five detectors.
Radiat Prot Dosimetry
; 199(15-16): 1968-1972, 2023 Oct 11.
Article
en En
| MEDLINE
| ID: mdl-37819306
ABSTRACT
In proton therapy, most treatment planning systems (TPS) use a fixed relative biological effectiveness (RBE) of 1.1 all along the depth-dose profile. Innovative TPS are now investigated considering the variability of RBE with radiation quality. New TPS need an experimental verification in the quality assurance (QA) routine in clinics, but RBE data are usually obtained with radiobiological measurements that are time consuming and not suitable for daily QA. Microdosimetry is a useful tool based on physical measurements which can monitor the radiation quality. Several microdosimeters are available in different research institutions, which could potentially be used for the QA in TPS. In this study, the response functions of five detectors in the same 62-MeV proton Spread Out Bragg Peak is compared in terms of spectral distributions and their average values and microdosimetric RBE. Their different response function has been commented and must be considered in the clinical practice.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Protones
/
Terapia de Protones
Idioma:
En
Revista:
Radiat Prot Dosimetry
Año:
2023
Tipo del documento:
Article
País de afiliación:
Italia