The microbiome as a biomarker of anal precancerous lesions in people with HIV.
Curr Opin Infect Dis
; 37(1): 17-25, 2024 Feb 01.
Article
en En
| MEDLINE
| ID: mdl-37889583
ABSTRACT
PURPOSE OF REVIEW Early detection and treatment of human papillomavirus (HPV)-related anal dysplasia in some high-risk groups can help anal cancer prevention, but new tools to improve diagnostic and risk assessment are needed. Here, we aim to discuss the evidence on the role of the microbiome as a potential biomarker for anal high-grade squamous intraepithelial lesions (HSILs) in people with HIV (PWH). RECENT FINDINGS:
This review covers relevant studies on the links between the microbiome and HPV infection, cervical dysplasia/cancer, and anal HPV disease. It focuses on anal samples and precancerous lesions.SUMMARY:
The review highlights the promising potential of the anal microbiome as a novel biomarker for precancerous lesions in people with HIV, while also discussing limitations and future research needs.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias del Ano
/
Lesiones Precancerosas
/
Infecciones por VIH
/
Infecciones por Papillomavirus
Límite:
Female
/
Humans
Idioma:
En
Revista:
Curr Opin Infect Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2024
Tipo del documento:
Article