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Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers.
Jiagge, Evelyn; Jin, Dexter X; Newberg, Justin Y; Perea-Chamblee, Tomin; Pekala, Kelly R; Fong, Christopher; Waters, Michele; Ma, David; Dei-Adomakoh, Yvonne; Erb, Gilles; Arora, Kanika S; Maund, Sophia L; Njiraini, Njoki; Ntekim, Atara; Kim, Susie; Bai, Xuechun; Thomas, Marlene; van Eeden, Ronwyn; Hegde, Priti; Jee, Justin; Chakravarty, Debyani; Schultz, Nikolaus; Berger, Michael F; Frampton, Garrett M; Sokol, Ethan S; Carrot-Zhang, Jian.
Afiliación
  • Jiagge E; Hematology/Oncology Division, Department of Medicine, Henry Ford Health System, Detroit, MI, USA. Electronic address: ejiagge1@hfhs.org.
  • Jin DX; Computational Discovery, Foundation Medicine, Inc., Cambridge, MA, USA. Electronic address: djin@foundationmedicine.com.
  • Newberg JY; Computational Discovery, Foundation Medicine, Inc., Cambridge, MA, USA.
  • Perea-Chamblee T; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Pekala KR; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Fong C; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Waters M; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ma D; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Dei-Adomakoh Y; Department of Haematology, University of Ghana Medical School, Accra, Ghana.
  • Erb G; Global Product Development Medical Affairs - Oncology, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Arora KS; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer, New York, NY, USA.
  • Maund SL; Computational Sciences, Genentech, Inc., South San Francisco, CA, USA.
  • Njiraini N; Department of Oncology, Kenyatta University Teaching Research and Referral Hospital, Nairobi, Kenya.
  • Ntekim A; Department of Radiation Oncology, University of Ibadan, Ibadan, Nigeria.
  • Kim S; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Bai X; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Thomas M; Global Product Development Medical Affairs - Oncology, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • van Eeden R; Department of Medical Oncology, Chris Hani Academic Baragwanath Hospital, Johannesburg, South Africa.
  • Hegde P; Computational Discovery, Foundation Medicine, Inc., Cambridge, MA, USA.
  • Jee J; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chakravarty D; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer, New York, NY, USA; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Schultz N; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Berger MF; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer, New York, NY, USA; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Frampton GM; Computational Discovery, Foundation Medicine, Inc., Cambridge, MA, USA.
  • Sokol ES; Computational Discovery, Foundation Medicine, Inc., Cambridge, MA, USA.
  • Carrot-Zhang J; Computational Oncology, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Clinial Genetics, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: carrotj@mskcc.org.
Cancer Cell ; 41(11): 1963-1971.e3, 2023 11 13.
Article en En | MEDLINE | ID: mdl-37890492

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Neoplasias Pulmonares Límite: Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas Tirosina Quinasas / Neoplasias Pulmonares Límite: Humans / Male Idioma: En Revista: Cancer Cell Asunto de la revista: NEOPLASIAS Año: 2023 Tipo del documento: Article