The response time paradox in functional magnetic resonance imaging analyses.
Nat Hum Behav
; 8(2): 349-360, 2024 Feb.
Article
en En
| MEDLINE
| ID: mdl-37996498
ABSTRACT
Response times (RTs) are often the main signal of interest in cognitive psychology but are often ignored in functional MRI (fMRI) analyses. In fMRI analysis the intensity of the signal serves as a proxy for the intensity of local neuronal activity, but changes in either the intensity or the duration of neuronal activity can yield identical fMRI signals. Therefore, if RTs are ignored and pair with neuronal durations, fMRI results claiming intensity differences may be confounded by RTs. We show how ignoring RTs goes beyond this confound, where longer RTs are paired with larger activation estimates, to lesser-known issues where RTs become confounds in group-level analyses and, surprisingly, how the RT confound can induce other artificial group-level associations with variables that are not related to the condition contrast or RTs. We propose a new time-series model to address these issues and encourage increasing focus on what the widespread RT-based signal represents.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
Límite:
Humans
Idioma:
En
Revista:
Nat Hum Behav
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos