Metal-free synthesis of 1,3-dichloro-1,5-diarylpentan-5-ones <i>via</i> cascade oxidative radical addition of styrenes with CHCl<sub>3</sub>.

Liu, Min; Liu, Bifu; Wang, Qian; Feng, Kejun; Li, Yuanhua; Liu, Lixin; Tong, Jiaen

Metal-free synthesis of 1,3-dichloro-1,5-diarylpentan-5-ones via cascade oxidative radical addition of styrenes with CHCl₃.

Liu, Min; Liu, Bifu; Wang, Qian; Feng, Kejun; Li, Yuanhua; Liu, Lixin; Tong, Jiaen.

Afiliación

Liu M; School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, China. liubf@hzu.edu.cn.
Liu B; Guangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, Guangdong, P. R. China.
Wang Q; School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, China. liubf@hzu.edu.cn.
Feng K; Guangdong Provincial Key Laboratory of Electronic Functional Materials and Devices, Huizhou University, Huizhou 516001, Guangdong, P. R. China.
Li Y; School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, China. liubf@hzu.edu.cn.
Liu L; School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, China. liubf@hzu.edu.cn.
Tong J; School of Chemistry and Materials Engineering, Huizhou University, Huizhou 516007, China. liubf@hzu.edu.cn.

Org Biomol Chem ; 22(4): 699-702, 2024 Jan 24.

Article en En | MEDLINE | ID: mdl-37999925

ABSTRACT

ABSTRACT

A novel and efficient metal-free cascade oxidative radical addition of styrenes is developed for the construction of 1,3-dichloro-1,5-diarylpentan-5-ones. This protocol presents a practical one-pot procedure that delivers highly functionalized 1,3-dichloro-1,5-diarylpentan-5-ones in moderate-to-good yields with a broad substrate scope under mild conditions.

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: China

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