A human mesenchymal spheroid prototype to replace moderate severity animal procedures in leukaemia drug testing.

Wilson, Aaron; Hockney, Sean; Parker, Jessica; Angel, Sharon; Blair, Helen; Pal, Deepali

Wilson, Aaron; Hockney, Sean; Parker, Jessica; Angel, Sharon; Blair, Helen; Pal, Deepali.

Afiliación

Wilson A; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, UK, Newcastle upon Tyne, NE1 7RU, UK.
Hockney S; Applied Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK.
Parker J; Applied Sciences, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK.
Angel S; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, UK, Newcastle upon Tyne, NE1 7RU, UK.
Blair H; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, UK, Newcastle upon Tyne, NE1 7RU, UK.
Pal D; Wolfson Childhood Cancer Research Centre, Translational and Clinical Research Institute, Newcastle University, UK, Newcastle upon Tyne, NE1 7RU, UK.

F1000Res ; 11: 1280, 2022.

Article en En | MEDLINE | ID: mdl-38046539

Asunto(s)

Leucemia; Células Madre Mesenquimatosas; Humanos; Ratones; Animales; Esferoides Celulares; Recurrencia Local de Neoplasia; Técnicas de Cocultivo; Leucemia/metabolismo; Microambiente Tumoral

Palabras clave

3D models; Animal replacement; Preclinical models; cancer research; leukaemia

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia / Células Madre Mesenquimatosas Límite: Animals / Humans Idioma: En Revista: F1000Res Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido

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