Cholesterol-Mediated Coenzyme A Depletion in Catabolic Mutants of Mycobacteria Leads to Toxicity.

Brown, Kirstin L; Krekhno, Jessica M C; Xing, Shipei; Huan, Tao; Eltis, Lindsay D

Brown, Kirstin L; Krekhno, Jessica M C; Xing, Shipei; Huan, Tao; Eltis, Lindsay D.

Afiliación

Brown KL; Department of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver V6T 1Z3, Canada.
Krekhno JMC; Department of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver V6T 1Z3, Canada.
Xing S; Department of Chemistry, The University of British Columbia, Vancouver V6T 1Z1, Canada.
Huan T; Department of Chemistry, The University of British Columbia, Vancouver V6T 1Z1, Canada.
Eltis LD; Department of Microbiology and Immunology, Life Sciences Institute, The University of British Columbia, Vancouver V6T 1Z3, Canada.

ACS Infect Dis ; 10(1): 107-119, 2024 Jan 12.

Article en En | MEDLINE | ID: mdl-38054469

Asunto(s)

Mycobacterium tuberculosis; Espectrometría de Masas en Tándem; Cromatografía Liquida; Colesterol/metabolismo; Coenzima A/metabolismo

Palabras clave

CoASH; Mycobacterium tuberculosis; acyl-CoA; catabolism; cholesterol; toxicity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Espectrometría de Masas en Tándem / Mycobacterium tuberculosis Idioma: En Revista: ACS Infect Dis Año: 2024 Tipo del documento: Article País de afiliación: Canadá

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