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Mpox and Chickenpox Coinfection: Case Series From Southern Nigeria.
Mmerem, Juliet I; Umenzekwe, Chukwudi C; Johnson, Simon M; Onukak, Asukwo E; Chika-Igwenyi, Nneka M; Chukwu, Sunday K; Onyeaghala, Chizaram A; Ozougwu, Jideofor J; Alasia, Datonye; Ehiakhamen, Odianosen; Nwankwo, Henry M; Ezejiofor, Ogochukwu I; Unigwe, Uche S; Iroezindu, Michael O.
Afiliación
  • Mmerem JI; Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Enugu State, Nigeria.
  • Umenzekwe CC; Department of Internal Medicine, Nnamdi Azikwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
  • Johnson SM; Department of Internal Medicine, Federal University Teaching Hospital, Owerri, Imo State, Nigeria.
  • Onukak AE; Department of Internal Medicine, University of Uyo Teaching Hospital, Uyo, Akwa Ibom State, Nigeria.
  • Chika-Igwenyi NM; Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.
  • Chukwu SK; Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.
  • Onyeaghala CA; Department of Internal Medicine, University of Port-Harcourt Teaching Hospital, Port-Harcourt, Rivers State, Nigeria.
  • Ozougwu JJ; Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Enugu State, Nigeria.
  • Alasia D; Department of Internal Medicine, Federal University Teaching Hospital, Owerri, Imo State, Nigeria.
  • Ehiakhamen O; Department of Internal Medicine, University of Port-Harcourt Teaching Hospital, Port-Harcourt, Rivers State, Nigeria.
  • Nwankwo HM; National Mpox Emergency Operating Centre, National Centre for Disease Control, Abuja, Nigeria.
  • Ezejiofor OI; Department of Internal Medicine, Nnamdi Azikwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
  • Unigwe US; Department of Internal Medicine, Nnamdi Azikwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
  • Iroezindu MO; Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Enugu State, Nigeria.
J Infect Dis ; 229(Supplement_2): S260-S264, 2024 Mar 26.
Article en En | MEDLINE | ID: mdl-38058122
ABSTRACT

BACKGROUND:

We describe clinicoepidemiologic characteristics of mpox-chickenpox coinfection in Nigeria.

METHODS:

A retrospective cohort analysis was performed of confirmed mpox cases in Nigeria from January 2022 to March 2023. Mpox and chickenpox were confirmed by real-time polymerase chain reaction (RT-PCR).

RESULTS:

Of 94 (60.0%) suspected cases, 56 had confirmed mpox, of whom 16 (28.6%) had chickenpox coinfection. The median age of confirmed mpox cases was 29 years (interquartile range, 20-37 years), 24 were men (60.7%), 6 (10.7%) were bisexual, and 5 (8.9%) died. Mpox-chickenpox-coinfected patients had more complications than mpox-monoinfected cases (56.3% vs 22.5%, P = .015).

CONCLUSIONS:

The high frequency of mpox-chickenpox coinfection argues for accelerated access to mpox and chickenpox vaccines in Africa.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Varicela / Mpox / Coinfección Límite: Adult / Female / Humans / Male País/Región como asunto: Africa Idioma: En Revista: J Infect Dis Año: 2024 Tipo del documento: Article País de afiliación: Nigeria

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Varicela / Mpox / Coinfección Límite: Adult / Female / Humans / Male País/Región como asunto: Africa Idioma: En Revista: J Infect Dis Año: 2024 Tipo del documento: Article País de afiliación: Nigeria