Enhancing phase I dose-finding trials design through dynamic borrowing information and handling late-onset toxicity.

Yang, Wenyun; He, Ruyue; Sun, Yuehan; Yan, Fangrong; Wang, Fei

Yang, Wenyun; He, Ruyue; Sun, Yuehan; Yan, Fangrong; Wang, Fei.

Afiliación

Yang W; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
He R; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
Sun Y; College of Management and Economics, Tianjin University, Tianjin, China.
Yan F; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
Wang F; Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.

Front Pharmacol ; 14: 1266322, 2023.

Article en En | MEDLINE | ID: mdl-38074153

Palabras clave

dose-finding; late-onset toxicity; model-assisted designs; multisource exchangeability models; supplemental data

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Front Pharmacol Año: 2023 Tipo del documento: Article País de afiliación: China

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