2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identified.

Neto, Nuno G B; Suku, Meenakshi; Hoey, David A; Monaghan, Michael G

Neto, Nuno G B; Suku, Meenakshi; Hoey, David A; Monaghan, Michael G.

Afiliación

Neto NGB; Department of Mechanical, Manufacturing and Biomedical Engineering, Trinity College Dublin, Parsons Building, Dublin 2, Ireland.
Suku M; Trinity Centre for Biomedical Engineering, Trinity College Dublin, Dublin, Ireland.
Hoey DA; Department of Mechanical, Manufacturing and Biomedical Engineering, Trinity College Dublin, Parsons Building, Dublin 2, Ireland.
Monaghan MG; CURAM SFI Research Centre for Medical Devices, National University of Ireland, Galway, Ireland.

Stem Cell Res Ther ; 14(1): 364, 2023 12 12.

Article en En | MEDLINE | ID: mdl-38087380

Asunto(s)

Células Madre Mesenquimatosas; Osteogénesis; Humanos; Osteogénesis/genética; Ácido Láctico/metabolismo; Células Madre Mesenquimatosas/metabolismo; Diferenciación Celular/fisiología; Huesos; Células Cultivadas

Palabras clave

Differentiation; Glutaminolysis; Imaging; Mesenchymal stem cells; Metabolism; Non-invasive characterization; Osteogenesis; Tissue engineering

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteogénesis / Células Madre Mesenquimatosas Límite: Humans Idioma: En Revista: Stem Cell Res Ther Año: 2023 Tipo del documento: Article País de afiliación: Irlanda

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