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Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity in vitro and in vivo.
Dong, Sanfeng; Hu, Ke; Shi, Yulong; Wang, Guanli; Yu, Dandan; Zhao, Yitian; Zhang, Hui; Wang, Yingcong; Sun, Haiguo; Xu, Zhijian; Jia, Qi; Li, Yiming; Li, Yingxia; Li, Bo; Shi, Jumei; Zhu, Weiliang.
Afiliación
  • Dong S; State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China; School of Pharmacy,
  • Hu K; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
  • Shi Y; State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Wang G; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
  • Yu D; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Zhao Y; State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China.
  • Zhang H; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China.
  • Wang Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
  • Sun H; State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Xu Z; State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China.
  • Jia Q; Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China.
  • Li Y; Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Shanghai 201203, China.
  • Li Y; School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China.
  • Li B; State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China; State Key Laboratory of Natur
  • Shi J; Department of Hematology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai 200120, China. Electronic address: shijumei@tongji.edu.cn.
  • Zhu W; State Key Laboratory of Drug Research, Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China; University of Chinese Academy of Sciences, No.19A Yuquan Road, Beijing 100049, China. Electronic address: wlzhu@sim
Bioorg Med Chem Lett ; 98: 129590, 2024 Jan 15.
Article en En | MEDLINE | ID: mdl-38092072
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cantaridina / Mieloma Múltiple Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cantaridina / Mieloma Múltiple Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article