Development of radiotracers for riboflavin transporter 3 imaging in diseases-A brief overview.
J Labelled Comp Radiopharm
; 67(2): 77-81, 2024 Feb.
Article
en En
| MEDLINE
| ID: mdl-38131157
ABSTRACT
Riboflavin (RF, vitamin B2) plays a key role in metabolic oxidation-reduction reactions, especially in the mitochondrial reprogramming of energy metabolism. Riboflavin transporter 3 (RFVT3) is a vital section of the mitochondrial network and involved in riboflavin homeostasis and production of adenosine triphosphate (ATP). The abnormal expression of RFVT3 is closely associated with the occurrence and progression of multiple diseases. Therefore, it is vital to understand the riboflavin internalization pathway under pathological conditions by addressing the abnormal expression of RFVT3, which could be a highly valuable biomarker for the early diagnosis and effective therapy of various diseases.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteínas de Transporte de Membrana
/
Riboflavina
Idioma:
En
Revista:
J Labelled Comp Radiopharm
Año:
2024
Tipo del documento:
Article
País de afiliación:
China