Laryngeal graft after total laryngectomy in humans: A SWiM analysis.
Eur Ann Otorhinolaryngol Head Neck Dis
; 141(2): 81-85, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38135563
ABSTRACT
Evaluation of the results of laryngeal transplantation (LT) in humans. Analysis of 3 bibliographic databases with the keywords "larynx, transplantation, autograft". In total, 626 abstracts were read and 25 articles selected. The main objective was to analyze the characteristics of laryngeal transplant patients. The accessory objectives comprised analysis of operative technique, immunosuppressive treatment and results. Four articles were selected for analysis. Two patients were transplanted after total laryngectomy for laryngeal carcinoma and 2 after laryngeal trauma. Three of the 4 patients had true transplantation with arterial, venous and neural microanastomosis. Two patients were decannulated and the tracheostomy tube was maintained in the other 2. Three of the 4 patients had good-quality phonation and could feed without a gastric tube. One patient died of carcinoma progression and 1 patient had to be explanted 14 years after transplantation. The number of LTs reported is too small for scientific determination of the place of this intervention in laryngology. The published results could, at first sight, suggest that the future of LT is uncertain. However, several elements, also suggest that otolaryngologists should continue to take an interest in this technique.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Laríngeas
/
Laringectomía
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Laringe
Límite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Eur Ann Otorhinolaryngol Head Neck Dis
/
Eur. ann. otorhinolaryngol. head neck dis
/
European annals of otorhinolaryngology, head and neck diseases (Print)
Año:
2024
Tipo del documento:
Article