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Anti-SARS-CoV-2 Activity of a Polyphenolic Complex from Maackia amurensis.
Krylova, N V; Iunikhina, O V; Fedoreev, S A; Pott, A B; Persiyanova, E V; Mishchenko, N P; Tarbeeva, D V; Shchelkanov, M Y.
Afiliación
  • Krylova NV; G. P. Somov Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Vladivostok, Russia. krylovanatalya@gmail.com.
  • Iunikhina OV; G. P. Somov Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Vladivostok, Russia.
  • Fedoreev SA; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
  • Pott AB; G. P. Somov Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Vladivostok, Russia.
  • Persiyanova EV; G. P. Somov Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Vladivostok, Russia.
  • Mishchenko NP; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
  • Tarbeeva DV; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia.
  • Shchelkanov MY; G. P. Somov Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Vladivostok, Russia.
Bull Exp Biol Med ; 176(2): 187-190, 2023 Dec.
Article en En | MEDLINE | ID: mdl-38191881
ABSTRACT
We studied the ability of the polyphenolic complex from Maackia amurensis, the active substance of Maksar, to inhibit the cytopathogenic effect induced by the SARS-CoV-2 and to reduce the concentration of viral RNA in infected Vero E6 cells. Polyphenolic complex showed significant anti-SARS-CoV-2 activity and effectively inhibited viral replication by direct action on viral particles and the early stage of viral infection.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Animals Idioma: En Revista: Bull Exp Biol Med Año: 2023 Tipo del documento: Article País de afiliación: Rusia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: SARS-CoV-2 / COVID-19 Límite: Animals Idioma: En Revista: Bull Exp Biol Med Año: 2023 Tipo del documento: Article País de afiliación: Rusia