A review on Zika vaccine development.
Pathog Dis
; 822024 Feb 07.
Article
en En
| MEDLINE
| ID: mdl-38192053
ABSTRACT
Zika virus (ZIKV), which belongs to the Flavivirus family, is mainly transmitted via the bite of Aedes mosquitoes. In newborns, ZIKV infection can cause severe symptoms such as microcephaly, while in adults, it can lead to GuillainâBarré syndrome (GBS). Due to the lack of specific therapeutic methods against ZIKV, the development of a safe and effective vaccine is extremely important. Several potential ZIKV vaccines, such as live attenuated, inactivated, nucleic acid, viral vector, and recombinant subunit vaccines, have demonstrated promising outcomes in clinical trials involving human participants. Therefore, in this review, the recent developmental progress, advantages and disadvantages of these five vaccine types are examined, and practical recommendations for future development are provided.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Vacunas
/
Virus Zika
/
Infección por el Virus Zika
Tipo de estudio:
Guideline
Límite:
Adult
/
Animals
/
Humans
/
Newborn
Idioma:
En
Revista:
Pathog Dis
Año:
2024
Tipo del documento:
Article
País de afiliación:
China