Enhancing tissue imaging contrast in photoacoustic tomography using the ultrasound thermal effect.
Opt Lett
; 49(2): 234-237, 2024 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-38194536
ABSTRACT
Photoacoustic imaging is a powerful technique for obtaining high-resolution images of vascular distribution and physiological information about blood by utilizing the light absorption coefficient as an imaging contrast. However, visualizing weakly light-absorbing components without specific contrast agents or multi-wavelength techniques presents a challenge due to significant differences in light absorption between these components and blood. In this study, we propose a novel method that leverages the thermal effect of ultrasound to induce temperature differences and enhance the contrast of photoacoustic imaging. We conducted phantom experiments to verify the feasibility of our method. Our method effectively highlighted weakly light-absorbing components with strong acoustic absorption, even in the presence of highly light-absorbing components such as blood or melanin. Furthermore, it enabled the differentiation of components with similar light absorption but different acoustic absorption.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Acústica
/
Tomografía Computarizada por Rayos X
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Opt Lett
Año:
2024
Tipo del documento:
Article