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Exploring the Therapeutic Potential of Lawsone and Nanoparticles in Cancer and Infectious Disease Management.
Kamil Zaidan, Haider; Jasim Al-Khafaji, Hanadi Had; Al-Dolaimy, F; Abed Hussein, Shaymaa; Otbah Farqad, Rand; Thabit, Daha; Talib Kareem, Ashwaq; Ramadan, Montather F; Hamood, Sarah A; Alawadi, Ahmed Hussien; Alsaalamy, Ali.
Afiliación
  • Kamil Zaidan H; Nursing College, Al-Mustaqbal University, Hillah, Babylon, Iraq.
  • Jasim Al-Khafaji HH; College of Chemistry, The University of Jordan, Amman, Jordan.
  • Al-Dolaimy F; Al-Zahraa University for Women, Karbala, Iraq.
  • Abed Hussein S; Department of Medical Engineering, Al-Manara College for Medical Sciences, Maysan, Iraq.
  • Otbah Farqad R; Department of Dentistry, Al-Noor University College, Bartella, Iraq.
  • Thabit D; Medical Technical College, Al-Farahidi University, Baghdad, Iraq.
  • Talib Kareem A; College of Pharmacy, National University of Science and Technology, Dhi Qar, Iraq.
  • Ramadan MF; College of Dentistry, Al-Ayen University, Thi-Qar, Iraq.
  • Hamood SA; Department of Medical Engineering, Al-Esraa University College, Baghdad, Iraq.
  • Alawadi AH; College of Technical Engineering, The Islamic University, Najaf, Iraq.
  • Alsaalamy A; College of Technical Engineering, The Islamic University of Al Diwaniyah, Qadisiyyah, Iraq.
Chem Biodivers ; 21(4): e202301777, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38373183
ABSTRACT
Lawsone, a naturally occurring compound found in henna, has been used in traditional medicine for centuries due to its diverse biological activities. In recent years, its nanoparticle-based structure has gained attention in cancer and infectious disease research. This review explores the therapeutic potential of lawsone and its nanoparticles in the context of cancer and infectious diseases. Lawsone exhibits promising anticancer properties by inducing apoptosis and inhibiting cell proliferation, while its nanoparticle formulations enhance targeted delivery and efficacy. Moreover, lawsone demonstrates significant antimicrobial effects against various pathogens. The unique physicochemical properties of lawsone nanoparticles enable efficient cellular uptake and targeted delivery. Potential applications in combination therapy and personalized medicine open new avenues for cancer and infectious disease treatment. While clinical trials are needed to validate their safety and efficacy, lawsone-based nanoparticles offer hope in addressing unmet medical needs and revolutionizing therapeutic approaches.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Transmisibles / Naftoquinonas / Neoplasias Límite: Humans Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Irak

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Transmisibles / Naftoquinonas / Neoplasias Límite: Humans Idioma: En Revista: Chem Biodivers Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Irak