Using Pod Based e-Cigarettes and Nicotine Pouches to Reduce Harm for Adults With Low Socioeconomic Status Who Smoke: A Pilot Randomized Controlled Trial.
Nicotine Tob Res
; 26(9): 1150-1158, 2024 Aug 22.
Article
en En
| MEDLINE
| ID: mdl-38447095
ABSTRACT
INTRODUCTION:
Alternative Nicotine Delivery Systems (ANDS) such as e-cigarettes (EC) and oral nicotine pouches (ONP) may facilitate the substitution of smoking for those unwilling to quit. This pilot study assesses the harm-reduction potential of EC and ONP among smokers with low socioeconomic status (SES). AIMS ANDMETHODS:
Adults who smoked daily in the past 6 months, had a household incomeâ <â 250% federal poverty level and had no intention of quitting smoking in the next 30 days were randomized 221 to 8 weeks of 5% nicotine EC; 4 mg ONP or assessment-only control (CC). The primary outcome was a within-group change in cigarettes per day (CPD) from Baseline to week 8.RESULTS:
Forty-five individuals were randomized (EC Nâ =â 18; ONP Nâ =â 18; CC Nâ =â 9). Analyses included 33 participants who completed the week 8 visit. The mean age was 50.1 years (SD 10.7) and the average CPD at baseline was 13.9 (SD 10.1). For those randomized to EC, the average CPD decreased from 14.7 (95% CI 10.3 to 19.1) at the Baseline to 2.9 (95% CI .1 to 5.8) at week 8 (p-valueâ <â .001). For those randomized to ONP, average CPD decreased from 15.0 (95% CI 5.0 to 24.9) to 8.3 (95% CI 1.3 to 15.2) by week 8 (p-valueâ =â .01). In the EC and ONP groups, respectively, 4 (28.6%) and 1 (8.3%) participant fully switched from smoking to the ANDS product by week 8.CONCLUSIONS:
Individuals with low SES who smoke had lower CPD after switching to EC or ONP. These findings show the potential of ANDS in helping smokers switch to less harmful devices. IMPLICATIONS This study provides novel evidence that e-cigarettes and nicotine pouches can be a harm-reduction tool for individuals with lower SES who smoke and are not willing to quit smoking, contributing to reducing tobacco-related disparities in this population.Clinical Trials Identifier NCT05327439.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cese del Hábito de Fumar
/
Sistemas Electrónicos de Liberación de Nicotina
Límite:
Adult
/
Humans
/
Middle aged
Idioma:
En
Revista:
Nicotine Tob Res
Asunto de la revista:
SAUDE PUBLICA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos