A biomimetic approach to lycogarubin C, lynamicin D and related analogues.

Li, Wenxue; Liu, Sheng

Li, Wenxue; Liu, Sheng.

Afiliación

Li W; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China. lsheng@126.com.
Liu S; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guiyang 550014, China. lsheng@126.com.

Org Biomol Chem ; 22(13): 2558-2561, 2024 03 27.

Article en En | MEDLINE | ID: mdl-38450726

ABSTRACT

ABSTRACT

An efficient and biomimetic synthetic approach to 3,4-diindolylpyrrole-2,5-dicarboxylate derivatives, including lycogarubin C, lynamicin D and related analogues, was discovered. The crucial transformation included the one-pot formation of two C-N bonds and one C-C bond to construct characteristic pyrrole rings.

Asunto(s)

Biomimética; Pirroles; Pirroles/química; Indoles/química

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirroles / Biomimética Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: China

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