Genetic variation drives differences in obesity-related gene regulation.
Trends Genet
; 40(4): 296-298, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38462400
ABSTRACT
Heikkinen and colleagues recently demonstrated that genetic variation, rather than dietary changes, governs gene regulation in liver. This finding highlights the impact of noncoding variants on chromatin accessibility, histone modifications, transcription factor binding, and gene expression and has implications for future research directions in understanding the genetic basis of disease.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cromatina
/
Regulación de la Expresión Génica
Límite:
Humans
Idioma:
En
Revista:
Trends Genet
Asunto de la revista:
GENETICA
Año:
2024
Tipo del documento:
Article