Understanding the infection severity and epidemiological characteristics of mpox in the UK.
Nat Commun
; 15(1): 2199, 2024 Mar 11.
Article
en En
| MEDLINE
| ID: mdl-38467622
ABSTRACT
In May 2022, individuals infected with the monkeypox virus were detected in the UK without clear travel links to endemic areas. Understanding the clinical characteristics and infection severity of mpox is necessary for effective public health policy. The study period of this paper, from the 1st June 2022 to 30th September 2022, included 3,375 individuals that tested positive for the monkeypox virus. The posterior mean times from infection to hospital admission and length of hospital stay were 14.89 days (95% Credible Intervals (CrI) 13.60, 16.32) and 7.07 days (95% CrI 6.07, 8.23), respectively. We estimated the modelled Infection Hospitalisation Risk to be 4.13% (95% CrI 3.04, 5.02), compared to the overall sample Case Hospitalisation Risk (CHR) of 5.10% (95% CrI 4.38, 5.86). The overall sample CHR was estimated to be 17.86% (95% CrI 6.06, 33.11) for females and 4.99% (95% CrI 4.27, 5.75) for males. A notable difference was observed between the CHRs that were estimated for each sex, which may be indicative of increased infection severity in females or a considerably lower infection ascertainment rate. It was estimated that 74.65% (95% CrI 55.78, 86.85) of infections with the monkeypox virus in the UK were captured over the outbreak.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades del Nervio Abducens
/
Mpox
Límite:
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Nat Commun
Asunto de la revista:
BIOLOGIA
/
CIENCIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Reino Unido