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Insights on E1-like enzyme ATG7: functional regulation and relationships with aging-related diseases.
Liu, Jingwei; Xiao, Yutong; Cao, Liangzi; Lu, Songming; Zhang, Siyi; Yang, Ruohan; Wang, Yubang; Zhang, Naijin; Yu, Yang; Wang, Xiwen; Guo, Wendong; Wang, Zhuo; Xu, Hongde; Xing, Chengzhong; Song, Xiaoyu; Cao, Liu.
Afiliación
  • Liu J; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
  • Xiao Y; Key Laboratory of Cell Biology of Ministry of Public Health, Key Laboratory of Medical Cell Biology of Ministry of Education, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Liaoning Province Collaborative Innovation C
  • Cao L; Department of Anus and Intestine Surgery, First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
  • Lu S; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
  • Zhang S; Key Laboratory of Cell Biology of Ministry of Public Health, Key Laboratory of Medical Cell Biology of Ministry of Education, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Liaoning Province Collaborative Innovation C
  • Yang R; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
  • Wang Y; Key Laboratory of Cell Biology of Ministry of Public Health, Key Laboratory of Medical Cell Biology of Ministry of Education, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Liaoning Province Collaborative Innovation C
  • Zhang N; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
  • Yu Y; Key Laboratory of Cell Biology of Ministry of Public Health, Key Laboratory of Medical Cell Biology of Ministry of Education, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Liaoning Province Collaborative Innovation C
  • Wang X; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
  • Guo W; Key Laboratory of Cell Biology of Ministry of Public Health, Key Laboratory of Medical Cell Biology of Ministry of Education, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Liaoning Province Collaborative Innovation C
  • Wang Z; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
  • Xu H; Key Laboratory of Cell Biology of Ministry of Public Health, Key Laboratory of Medical Cell Biology of Ministry of Education, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Liaoning Province Collaborative Innovation C
  • Xing C; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
  • Song X; Key Laboratory of Cell Biology of Ministry of Public Health, Key Laboratory of Medical Cell Biology of Ministry of Education, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors (China Medical University), Ministry of Education, Liaoning Province Collaborative Innovation C
  • Cao L; The College of Basic Medical Science, Health Sciences Institute, China Medical University, Shenyang, Liaoning, China.
Commun Biol ; 7(1): 382, 2024 Mar 29.
Article en En | MEDLINE | ID: mdl-38553562
ABSTRACT
Autophagy is a dynamic self-renovation biological process that maintains cell homeostasis and is responsible for the quality control of proteins, organelles, and energy metabolism. The E1-like ubiquitin-activating enzyme autophagy-related gene 7 (ATG7) is a critical factor that initiates classic autophagy reactions by promoting the formation and extension of autophagosome membranes. Recent studies have identified the key functions of ATG7 in regulating the cell cycle, apoptosis, and metabolism associated with the occurrence and development of multiple diseases. This review summarizes how ATG7 is precisely programmed by genetic, transcriptional, and epigenetic modifications in cells and the relationship between ATG7 and aging-related diseases.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Autofagosomas Idioma: En Revista: Commun Biol Año: 2024 Tipo del documento: Article País de afiliación: China
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Autofagia / Autofagosomas Idioma: En Revista: Commun Biol Año: 2024 Tipo del documento: Article País de afiliación: China