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Adipose exosomal noncoding RNAs: Roles and mechanisms in metabolic diseases.
Wu, Yan-Lin; Lin, Zheng-Jun; Li, Chang-Chun; Lin, Xiao; Shan, Su-Kang; Guo, Bei; Zheng, Ming-Hui; Wang, Yi; Li, Fuxingzi; Yuan, Ling-Qing.
Afiliación
  • Wu YL; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Lin ZJ; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Li CC; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Lin X; Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Shan SK; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Guo B; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Zheng MH; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Wang Y; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Li F; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Yuan LQ; National Clinical Research Center for Metabolic Disease, Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Obes Rev ; 25(6): e13740, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38571458
ABSTRACT
Exosomes are extracellular vesicles, measuring 40-160 nm in diameter, that are released by many cell types and tissues, including adipose tissue. Exosomes are critical mediators of intercellular communication and their contents are complex and diverse. In recent years, accumulating evidence has proved that multiple adipose tissue-derived exosomal noncoding RNAs (ncRNAs), including microRNAs (miRNAs), long noncoding RNAs (lncRNAs) and circular RNAs (circRNAs), play pivotal roles in the pathogenesis of diverse metabolic diseases, such as obesity. In this narrative review, we focus on the adipose tissue-derived exosomal ncRNAs, especially exosomal miRNAs, and their dysregulation in multiple types of metabolic diseases. A deeper understanding of the role of adipose tissue-derived exosomal ncRNAs may help provide new diagnostic and treatment methods for metabolic diseases.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tejido Adiposo / ARN no Traducido / Exosomas / Enfermedades Metabólicas Límite: Animals / Humans Idioma: En Revista: Obes Rev Asunto de la revista: METABOLISMO Año: 2024 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tejido Adiposo / ARN no Traducido / Exosomas / Enfermedades Metabólicas Límite: Animals / Humans Idioma: En Revista: Obes Rev Asunto de la revista: METABOLISMO Año: 2024 Tipo del documento: Article País de afiliación: China