Rapid response to dupilumab in an adult patient with eosinophilic esophagitis and allergic asthma.
Allergol Select
; 8: 78-81, 2024.
Article
en En
| MEDLINE
| ID: mdl-38601814
ABSTRACT
BACKGROUND:
Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus that belongs to the spectrum of Th2-mediated diseases. It is often associated with atopic comorbidities such as allergic asthma (AA) and poses a therapeutic challenge. CASE REPORT We report on a 43-year-old patient with EoE and AA who did not show sufficient therapeutic control despite standard therapy. We started treatment with dupilumab, whereupon both EoE and AA rapidly improved and complete symptom resolution could be documented. The response to dupilumab was assessed by laboratory monitoring and gastroscopy, which showed a reduction of markers of type II inflammation and eosinophilic infiltrates in the esophagus.SUMMARY:
Our report emphasizes the effective and safe use of dupilumab as a treatment option for EoE with concomitant beneficial effects on AA.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Allergol Select
Año:
2024
Tipo del documento:
Article
País de afiliación:
Alemania