[Cerebral oxygen metabolism and brain electrical activity of healthy full-term neonates in high-altitude areas: a multicenter clinical research protocol]. / é«æµ·æå°åºå¥åº·è¶³ææ°çå¿è氧代谢åèçµæ´»å¨å·®å¼çå¤ä¸å¿ä¸´åºç 究æ¹æ¡.
Zhongguo Dang Dai Er Ke Za Zhi
; 26(4): 403-409, 2024 Apr 15.
Article
en Zh
| MEDLINE
| ID: mdl-38660905
ABSTRACT
Further evidence is needed to explore the impact of high-altitude environments on the neurologic function of neonates. Non-invasive techniques such as cerebral near-infrared spectroscopy and amplitude-integrated electroencephalography can provide data on cerebral oxygenation and brain electrical activity. This study will conduct multiple cerebral near-infrared spectroscopy and amplitude-integrated electroencephalography monitoring sessions at various time points within the first 3 days postpartum for healthy full-term neonates at different altitudes. The obtained data on cerebral oxygenation and brain electrical activity will be compared between different altitudes, and corresponding reference ranges will be established. The study involves 6 participating centers in the Chinese High Altitude Neonatal Medicine Alliance, with altitude gradients divided into 4 categories 800 m, 1 900 m, 2 400 m, and 3 500 m, with an anticipated sample size of 170 neonates per altitude gradient. This multicenter prospective cohort study aims to provide evidence supporting the impact of high-altitude environments on early brain function and metabolism in neonates.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Oxígeno
/
Encéfalo
/
Electroencefalografía
/
Altitud
Límite:
Humans
/
Newborn
Idioma:
Zh
Revista:
Zhongguo Dang Dai Er Ke Za Zhi
/
Zhongguo dangdai erke zazhi
Año:
2024
Tipo del documento:
Article
País de afiliación:
China