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Cabotegravir and rilpivirine long acting injectables in a pregnant woman living with HIV.
van der Wekken-Pas, Lena; Weiss, Fabian; Simon-Zuber, Charlotte; Sebisch, Rena; Wiese, Carmen; van Leeuwen, Elisabeth; Burger, David; Colbers, Angela.
Afiliación
  • van der Wekken-Pas L; Radboud university medical center, department of pharmacy, Radboud Institute for Medical Innovations (RIMI), Nijmegen, the Netherlands.
  • Weiss F; Department of Obstetrics and Gynecology, LMU university hospital, LMU Munich, Germany.
  • Simon-Zuber C; Department of Obstetrics and Gynecology, LMU university hospital, LMU Munich, Germany.
  • Sebisch R; Department of Obstetrics and Gynecology, LMU university hospital, LMU Munich, Germany.
  • Wiese C; MVZ München am Goetheplatz, Munich, Germany.
  • van Leeuwen E; Amsterdam university medical center, department of gynecology, Amsterdam, the Netherlands.
  • Burger D; Radboud university medical center, department of pharmacy, Radboud Institute for Medical Innovations (RIMI), Nijmegen, the Netherlands.
  • Colbers A; Radboud university medical center, department of pharmacy, Radboud Institute for Medical Innovations (RIMI), Nijmegen, the Netherlands.
Clin Infect Dis ; 2024 May 03.
Article en En | MEDLINE | ID: mdl-38703388
ABSTRACT
This case report describes bimonthly LAI CAB/RPV prior to and throughout pregnancy. CAB concentration was comparable to non-pregnant individuals, RPV was 70-75% lower. No virologic failure orvertical transmission occurred. Despite placental transfer, no congenital malformations were noted. Bimonthly CAB/RPV LAI may not be suitable for pregnant women and monitoring of exposed infants is warranted.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Clin Infect Dis Asunto de la revista: DOENCAS TRANSMISSIVEIS Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos