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Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning.
Laubscher, Emily; Wang, Xuefei; Razin, Nitzan; Dougherty, Tom; Xu, Rosalind J; Ombelets, Lincoln; Pao, Edward; Graf, William; Moffitt, Jeffrey R; Yue, Yisong; Van Valen, David.
Afiliación
  • Laubscher E; Division of Chemistry and Chemical Engineering, Caltech, Pasadena, CA 91125, USA.
  • Wang X; Division of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.
  • Razin N; Division of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.
  • Dougherty T; Division of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.
  • Xu RJ; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02115, USA.
  • Ombelets L; Division of Chemistry and Chemical Engineering, Caltech, Pasadena, CA 91125, USA.
  • Pao E; Division of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.
  • Graf W; Division of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA.
  • Moffitt JR; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Yue Y; Division of Computational and Mathematical Sciences, Caltech, Pasadena, CA 91125, USA.
  • Van Valen D; Division of Biology and Biological Engineering, Caltech, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: vanvalen@caltech.edu.
Cell Syst ; 15(5): 475-482.e6, 2024 May 15.
Article en En | MEDLINE | ID: mdl-38754367
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Hibridación Fluorescente in Situ / Perfilación de la Expresión Génica / Transcriptoma / Aprendizaje Profundo Límite: Animals / Humans Idioma: En Revista: Cell Syst Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Hibridación Fluorescente in Situ / Perfilación de la Expresión Génica / Transcriptoma / Aprendizaje Profundo Límite: Animals / Humans Idioma: En Revista: Cell Syst Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos