Putting the brakes on axonal branching.
Trends Neurosci
; 47(7): 475-477, 2024 Jul.
Article
en En
| MEDLINE
| ID: mdl-38760194
ABSTRACT
In a recent study, Ziak et al. employed precise sparse labeling and spatiotemporally controlled genetic manipulations to uncover novel regulators of axon branching of layer 2/3 mouse callosal projection neurons. The authors elucidated a cell-autonomous signaling pathway wherein glycogen synthase kinase 3ß (GSK3ß) phosphorylation of microtubule-associated protein 1B (MAP1B) restricts interstitial axon branching by modulating microtubule (MT) tyrosination status.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Axones
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Neurosci
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos