LLL 44-4 : Micronutrients in acute disease and critical illness.
Clin Nutr ESPEN
; 61: 437-446, 2024 Jun.
Article
en En
| MEDLINE
| ID: mdl-38777466
ABSTRACT
Micronutrients (MN), i.e. trace elements and vitamins, are essential components of the diet in relatively small amounts in any form of nutrition, with special needs in critically ill patients. Critical illness is characterised by the presence of inflammation and oxidative stress. MNs are tightly involved in antioxidant and immune defences. In addition, some conditions, and treatments result in large losses of biological fluids containing MNs therefore, acute renal injury requiring renal replacement therapy, acute intestinal failure, and major burns and trauma are at high risk of acute depletion of body stores, and of deficiency. MN requirements are increased above standard DRI. Blood level interpretation is complicated by inflammation some biomarkers assist the status determination. Due to the acute challenges of critical illness, it of utmost importance to cover the needs to maintain the organism's endogenous immune and antioxidant defences, and capacity to repair tissues. Practical strategies are proposed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad Crítica
/
Estrés Oxidativo
/
Micronutrientes
Límite:
Humans
Idioma:
En
Revista:
Clin Nutr ESPEN
Año:
2024
Tipo del documento:
Article