Generation of an iPSC line from a 79-year-old female patient diagnosed with sporadic Parkinson's disease.
Stem Cell Res
; 78: 103450, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38820865
ABSTRACT
Parkinson's disease is a common neurodegenerative disorder. Here we present a human induced pluripotent stem cells (iPSCs) derived from peripheral blood mononuclear cells (PBMCs) of a 79-year-old female patient diagnosed with sporadic Parkinson's disease using the sendai virus. Generated iPSCs maintain normal karyotype, exhibit pluripotent stem cell markers, and possess differentiation potential. The iPSCs allows for differentiation into various cell subtypes, providing conditions for the research of the pathogenesis and drug development of Parkinson's disease.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad de Parkinson
/
Diferenciación Celular
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Células Madre Pluripotentes Inducidas
Límite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Stem Cell Res
Año:
2024
Tipo del documento:
Article
País de afiliación:
China