Granulomatous Panniculitis as an Initial Manifestation of Sjögren Syndrome.
Am J Dermatopathol
; 46(8): 523-524, 2024 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-38842395
ABSTRACT
ABSTRACT A 65-year-old woman presented with unexplained weight loss, recurrent fever, and a dermatosis with painful nodules on the extremities. Biopsies showed focal lobular panniculitis with neutrophilic microgranulomas. Comprehensive investigations ruled out infection and hematologic and solid organ neoplasms. Laboratory results showed anti-Ro/SSA and anti-La/SSB antibody positivity, and elevated inflammatory markers. Dry mouth and eye were confirmed. The diagnosis of Sjögren syndrome with cutaneous panniculitis was established. Prednisone treatment with 30 mg/d resulted in remission of fever and pain improvement. This case emphasizes Sjögren syndrome as an autoimmune disease with multiple cutaneous manifestations and highlights its association with granulomatous panniculitis.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Paniculitis
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Síndrome de Sjögren
Límite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Am J Dermatopathol
Año:
2024
Tipo del documento:
Article
País de afiliación:
México