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Improving laboratory animal genetic reporting: LAG-R guidelines.
Teboul, Lydia; Amos-Landgraf, James; Benavides, Fernando J; Birling, Marie-Christine; Brown, Steve D M; Bryda, Elizabeth; Bunton-Stasyshyn, Rosie; Chin, Hsian-Jean; Crispo, Martina; Delerue, Fabien; Dobbie, Michael; Franklin, Craig L; Fuchtbauer, Ernst-Martin; Gao, Xiang; Golzio, Christelle; Haffner, Rebecca; Hérault, Yann; Hrabe de Angelis, Martin; Lloyd, Kevin C Kent; Magnuson, Terry R; Montoliu, Lluis; Murray, Stephen A; Nam, Ki-Hoan; Nutter, Lauryl M J; Pailhoux, Eric; Pardo Manuel de Villena, Fernando; Peterson, Kevin; Reinholdt, Laura; Sedlacek, Radislav; Seong, Je Kyung; Shiroishi, Toshihiko; Smith, Cynthia; Takeo, Toru; Tinsley, Louise; Vilotte, Jean-Luc; Warming, Søren; Wells, Sara; Whitelaw, C Bruce; Yoshiki, Atsushi; Pavlovic, Guillaume.
Afiliación
  • Teboul L; The Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, OX11 0RD, Oxon, UK. l.teboul@har.mrc.ac.uk.
  • Amos-Landgraf J; University of Missouri School of Medicine, Columbia, MO, USA.
  • Benavides FJ; University of Missouri College of Veterinary Medicine, Columbia, MO, USA.
  • Birling MC; Rat Resource and Research Center, University of Missouri, Columbia, MO, USA.
  • Brown SDM; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bryda E; PHENOMIN-Institut Clinique de la Souris, CELPHEDIA, CNRS, INSERM, Université de Strasbourg, Illkirch-Grafenstaden, 67404, Strasbourg, France.
  • Bunton-Stasyshyn R; Visiting Scientist, Institut Clinique de la Souris, Université de Strasbourg, Illkirch-Grafenstaden, 67404, Strasbourg, France.
  • Chin HJ; Rat Resource and Research Center, University of Missouri, Columbia, MO, 65201, USA.
  • Crispo M; The Mary Lyon Centre at MRC Harwell, Harwell Campus, Didcot, OX11 0RD, Oxon, UK.
  • Delerue F; National Laboratory Animal Center (NLAC), NARLabs, Taipei, Taiwan.
  • Dobbie M; Laboratory Animal Biotechnology Unit, Institut Pasteur de Montevideo, Mataojo 2020, CP 1400, Montevideo, Uruguay.
  • Franklin CL; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Fuchtbauer EM; Phenomics Australia, Australian National University, 131 Garran Road, Canberra, ACT 2601, Australia.
  • Gao X; University of Missouri Mutant Mouse Resource and Research Center (MU MMRRC), University of Missouri, Columbia, MO, 65201, USA.
  • Golzio C; Department of Molecular Biology, University of Aarhus, Aarhus C, 8000, Denmark.
  • Haffner R; National Resource Center of Mutant Mice (NRCMM), Nanjing Biomedical Research Institute, Nanjing University, Nanjing, China.
  • Hérault Y; Université de Strasbourg, CNRS, Inserm, IGBMC UMR 7104- UMR-S 1258, F-67400, Illkirch, France.
  • Hrabe de Angelis M; Department Veterinary Resources, Weizmann Institute of Science, Rehovot, Israel.
  • Lloyd KCK; PHENOMIN-Institut Clinique de la Souris, CELPHEDIA, CNRS, INSERM, Université de Strasbourg, Illkirch-Grafenstaden, 67404, Strasbourg, France.
  • Magnuson TR; Université de Strasbourg, CNRS, Inserm, IGBMC UMR 7104- UMR-S 1258, F-67400, Illkirch, France.
  • Montoliu L; Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstaedter Landstraße 1, 85764, Neuherberg, Germany.
  • Murray SA; Chair of Experimental Genetics, TUM School of Life Sciences, Technische Universität München, Alte Akademie 8, 85354, Freising, Germany.
  • Nam KH; German Center for Diabetes Research (DZD), Ingolstaedter Landstraße 1, 85764, Neuherberg, Germany.
  • Nutter LMJ; Mouse Biology Program, University of California Davis, Davis, CA, USA.
  • Pailhoux E; Department of Genetics, and Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599-7264, USA.
  • Pardo Manuel de Villena F; Department of Molecular and Cellular Biology, National Centre for Biotechnology (CNB-CSIC), 28049, Madrid, Spain.
  • Peterson K; Centre for Biomedical Network Research on Rare Diseases (CIBERER-ISCIII), 28029, Madrid, Spain.
  • Reinholdt L; The Jackson Laboratory, Bar Harbor, ME, USA.
  • Sedlacek R; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Korea.
  • Seong JK; Genetics and Genome Biology, The Hospital for Sick Children and The Centre for Phenogenomics, Toronto, ON, M5T 3H7, Canada.
  • Shiroishi T; Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France.
  • Smith C; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA.
  • Takeo T; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, 27599, USA.
  • Tinsley L; The Jackson Laboratory, Bar Harbor, ME, USA.
  • Vilotte JL; The Jackson Laboratory, Bar Harbor, ME, USA.
  • Warming S; Czech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
  • Wells S; Laboratory of Developmental Biology and Genomics, BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, and Korea Mouse Phenotyping Center, Seoul, 08826, Republic of Korea.
  • Whitelaw CB; RIKEN BioResource Research Center (BRC), Tsukuba, Japan.
  • Yoshiki A; Mouse Genome Informatics (MGI), Jackson Laboratory, Bar Harbor, ME, USA.
Nat Commun ; 15(1): 5574, 2024 Jul 02.
Article en En | MEDLINE | ID: mdl-38956430
ABSTRACT
The biomedical research community addresses reproducibility challenges in animal studies through standardized nomenclature, improved experimental design, transparent reporting, data sharing, and centralized repositories. The ARRIVE guidelines outline documentation standards for laboratory animals in experiments, but genetic information is often incomplete. To remedy this, we propose the Laboratory Animal Genetic Reporting (LAG-R) framework. LAG-R aims to document animals' genetic makeup in scientific publications, providing essential details for replication and appropriate model use. While verifying complete genetic compositions may be impractical, better reporting and validation efforts enhance reliability of research. LAG-R standardization will bolster reproducibility, peer review, and overall scientific rigor.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Guías como Asunto / Animales de Laboratorio Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Guías como Asunto / Animales de Laboratorio Límite: Animals Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido