Zafirlukast induces DNA condensation and has bactericidal effect on replicating <i>Mycobacterium abscessus</i>.

Niet, Sanne van der; Green, Keith D; Schimmel, Irene M; Bakker, Jordy de; Lodder, Bastiaan; Reits, Eric A; Garneau-Tsodikova, Sylvie; van der Wel, Nicole N

Zafirlukast induces DNA condensation and has bactericidal effect on replicating Mycobacterium abscessus.

Niet, Sanne van der; Green, Keith D; Schimmel, Irene M; Bakker, Jordy de; Lodder, Bastiaan; Reits, Eric A; Garneau-Tsodikova, Sylvie; van der Wel, Nicole N.

Afiliación

Niet Svd; Electron Microscopy Centre Amsterdam, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Green KD; College of Pharmacy, University of Kentucky, Lexington, Kentucky, USA.
Schimmel IM; Electron Microscopy Centre Amsterdam, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Bakker Jd; Electron Microscopy Centre Amsterdam, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Lodder B; Electron Microscopy Centre Amsterdam, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Reits EA; Electron Microscopy Centre Amsterdam, Amsterdam University Medical Centre, Amsterdam, the Netherlands.
Garneau-Tsodikova S; College of Pharmacy, University of Kentucky, Lexington, Kentucky, USA.
van der Wel NN; Electron Microscopy Centre Amsterdam, Amsterdam University Medical Centre, Amsterdam, the Netherlands.

Antimicrob Agents Chemother ; 68(8): e0002924, 2024 Aug 07.

Article en En | MEDLINE | ID: mdl-38990015

Asunto(s)

Antibacterianos; Pruebas de Sensibilidad Microbiana; Mycobacterium abscessus; Fenilcarbamatos; Sulfonamidas; Compuestos de Tosilo; Mycobacterium abscessus/efectos de los fármacos; Mycobacterium abscessus/genética; Antibacterianos/farmacología; Compuestos de Tosilo/farmacología; Sulfonamidas/farmacología; Fenilcarbamatos/farmacología; Indoles/farmacología; Humanos; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; ADN Bacteriano/genética

Palabras clave

Mycobacterium abscessus; antibiotics; electron microscopy; zafirlukast

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Compuestos de Tosilo / Pruebas de Sensibilidad Microbiana / Fenilcarbamatos / Mycobacterium abscessus / Antibacterianos Límite: Humans Idioma: En Revista: Antimicrob Agents Chemother Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos

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