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An updated review on 1,2,3-/1,2,4-triazoles: synthesis and diverse range of biological potential.
Raman, Anirudh Pratap Singh; Aslam, Mohd; Awasthi, Amardeep; Ansari, Anas; Jain, Pallavi; Lal, Kashmiri; Bahadur, Indra; Singh, Prashant; Kumari, Kamlesh.
Afiliación
  • Raman APS; Department of Chemistry, Atma Ram Sanatan Dharma College, University of Delhi, Dhaula Kuan, New Delhi, India.
  • Aslam M; Department of Chemistry, SRM Institute of Science & Technology, Delhi-NCR Campus, Ghaziabad, Modinagar, India.
  • Awasthi A; Department of Chemistry, Atma Ram Sanatan Dharma College, University of Delhi, Dhaula Kuan, New Delhi, India.
  • Ansari A; Department of Chemistry, SRM Institute of Science & Technology, Delhi-NCR Campus, Ghaziabad, Modinagar, India.
  • Jain P; Department of Chemistry, North western University, Evanston, IL, USA.
  • Lal K; Department of Chemistry, North western University, Evanston, IL, USA.
  • Bahadur I; Department of Chemistry, SRM Institute of Science & Technology, Delhi-NCR Campus, Ghaziabad, Modinagar, India.
  • Singh P; Department of Chemistry, Guru Jambheshwar of Science and Technology, Hisar, India.
  • Kumari K; Department of Chemistry, Faculty of Natural and Agricultural Sciences, North-West University, Mafikeng Campus, Mmabatho, 2745, South Africa.
Mol Divers ; 2024 Jul 27.
Article en En | MEDLINE | ID: mdl-39066993
ABSTRACT
The synthesis of triazoles has attracted a lot of interest in the field of organic chemistry because of its versatile chemical characteristics and possible biological uses. This review offers an extensive overview of the different pathways used in the production of triazoles. A detailed analysis of recent research indicates that triazole compounds have a potential range of pharmacological activities, including the ability to inhibit enzymes, and have antibacterial, anticancer, and antifungal activities. The integration of computational and experimental methods provides a thorough understanding of the structure-activity connection, promoting sensible drug design and optimization. By including triazoles as essential components in drug discovery, researchers can further explore and innovate in the synthesis, biological assessment, and computational studies of triazoles as drugs, exploring the potential therapeutic significance of triazoles.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Mol Divers Asunto de la revista: BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article País de afiliación: India

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: Mol Divers Asunto de la revista: BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article País de afiliación: India