Immunohistochemical localization of beta-lipotropic hormone in the pituitary gland.
Endocrinology
; 100(3): 770-6, 1977 Mar.
Article
en En
| MEDLINE
| ID: mdl-401361
ABSTRACT
Identification of the beta-lipotropic hormone (beta-LPH)-producing cells in several species, including man, was performed with the technique involving use of the unlabeled antibody and peroxidase-antiperoxidase complex. Serial paraffin and ultrathin sections were treated for detection of both beta-LPH and ACTH at the light and electron microscopic levels. It was clearly shown that beta-LPH could be found only in the corticotropic cells located in the pars intermedia and pars distalis of all species studied. At the electron microscope level, it could be established that beta-LPH is contained in all the secretory granules of positive cells. These results suggest that beta-LPH is stored in the same secretory granules as ACTH and that both hormones are released together during granule extrusion.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hipófisis
/
Beta-Lipotropina
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Endocrinology
Año:
1977
Tipo del documento:
Article
País de afiliación:
Canadá