Paraneoplastic cerebellar disease. Remission with excision of the primary tumor.
Arch Neurol
; 42(12): 1208-10, 1985 Dec.
Article
en En
| MEDLINE
| ID: mdl-4062621
ABSTRACT
We describe two patients with paraneoplastic cerebellar syndromes who gained clinically useful neurologic remissions following radical excision of the primary cancer. In both patients the syndrome was characterized by the rapid onset of gait ataxia, nausea, postural vertigo, central positional nystagmus, and saccadic oscillations. These observations encourage radical treatment of the primary cancer in patients with advanced malignant neoplasms who are disabled by cerebellar dysfunction, and lend support to a current hypothesis that paraneoplastic cerebellar degeneration is due to anticerebellar Purkinje cell antibodies elaborated by the primary cancer.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Síndromes Paraneoplásicos
/
Neoplasias Retroperitoneales
/
Neoplasias Óseas
/
Adenocarcinoma
/
Enfermedades Cerebelosas
/
Condrosarcoma
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Arch Neurol
Año:
1985
Tipo del documento:
Article