Phosphonate analogue of 2'-deoxy-5-fluorouridylic acid.
J Med Chem
; 22(1): 109-11, 1979 Jan.
Article
en En
| MEDLINE
| ID: mdl-423172
The phosphonate analogue (6) of 2'-deoxy-5-fluorouridylic acid has been prepared via a Pfitzner--Moffatt oxidation and Witting reaction. This compound was found to inhibit thymidylate synthetase from three sources and to be cytotoxic to H.Ep.-2 cells in culture.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Nucleótidos de Desoxiuracil
/
Fluorodesoxiuridilato
Idioma:
En
Revista:
J Med Chem
Asunto de la revista:
QUIMICA
Año:
1979
Tipo del documento:
Article