Lymphocyte fluorescent profiles (LFP): a possible screening technique in neoplasia.
Cancer Lett
; 6(6): 357-64, 1979 May.
Article
en En
| MEDLINE
| ID: mdl-455274
ABSTRACT
A technique involving fluorescent protein staining and microfluorometry has been developed for measuring the lymphocyte fluorescent profile (LFP) of peripheral blood lymphocytes. In contrast to normal humans who display a regular bell-shaped curve, the profile from patients with cancer is irregular, showing a bimodal distribution of fluorescence, with a significant population of cells fluorescing at a higher relative intensity. It is suggested that this elevation in protein concentration is due to an immune response to the presence of a neoplasm, and thus this technique may prove to be a useful indicator of malignancy.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Linfocitos
/
Proteínas de Neoplasias
/
Neoplasias
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cancer Lett
Año:
1979
Tipo del documento:
Article