The metabolism of methoxyethylmercury salts.
Biochem J
; 121(3): 411-5, 1971 Feb.
Article
en En
| MEDLINE
| ID: mdl-5119773
ABSTRACT
The metabolism of methoxy[(14)C]ethylmercury chloride in the rat has been investigated. After a single subcutaneous dose a small proportion is excreted unchanged in urine and a larger amount in bile with some resorption from the gut. The greater part of the dose is rapidly broken down in the tissues with a half-time of about 1 day to yield ethylene and inorganic mercury. Ethylene is exhaled in the breath and the mercury migrates to the kidney and is excreted in urine. A small proportion of the dose appears as carbon dioxide in the breath and about 12% in urine as a mercury-free metabolite. It is possible that the breakdown of methoxyethylmercurychloride to ethylene and inorganic mercury is not catalysed by an enzyme system.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Compuestos Organometálicos
/
Mercurio
Límite:
Animals
Idioma:
En
Revista:
Biochem J
Año:
1971
Tipo del documento:
Article