Ascorbate stimulation of salicylate absorption in isolated rat intestine.
J Pharm Sci
; 67(2): 224-6, 1978 Feb.
Article
en En
| MEDLINE
| ID: mdl-621642
ABSTRACT
Salicylate transport across the rat intestine was measured using both in vitro and in vivo procedures. After the steady state for labeled salicylate was reached, the addition of ascorbate stimulated tracer flux with the establishment of a new steady state. The tissue permeability had a saturable dependence on ascorbate concentration. Also, ascorbate stimulated the tissue short-circuit current.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ácido Ascórbico
/
Salicilatos
/
Absorción Intestinal
Límite:
Animals
Idioma:
En
Revista:
J Pharm Sci
Año:
1978
Tipo del documento:
Article