Serum vitamin E levels in children with corrected biliary atresia.
Am J Clin Nutr
; 40(2): 246-50, 1984 Aug.
Article
en En
| MEDLINE
| ID: mdl-6465057
ABSTRACT
In 37 children with long-standing cholestasis who had undergone a Kasai's procedure (double Roux-en-Y hepatic portoenterostomy), serum vitamin E levels were determined. In addition, serum bile acid levels were simultaneously tested as a marker of cholestasis. Eighteen of 37 children had vitamin E levels of less than 0.50 mg/100 ml, and two showed neurological abnormalities including hypoactive deep tendon reflexes and ataxia. Serum vitamin E levels were inversely correlated with serum bile acid levels (p less than 0.01). Older patients have mild cholestasis and high serum vitamin E levels in comparison with younger ones. Improvement in bile excretion into the intestinal tract with age seemed to be responsible for an increase of serum vitamin E levels. Oral supplements of alpha-tocopherol in doses of 5 to 10 mg/kg/day were needed to maintain the normal serum vitamin E levels in postoperative infants.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Vitamina E
/
Conductos Biliares
Tipo de estudio:
Etiology_studies
Límite:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Am J Clin Nutr
Año:
1984
Tipo del documento:
Article