Pancreatic hydrolases in cold-induced hyperphagia of rats fed a low or high-fat diet.
Reprod Nutr Dev (1980)
; 23(1): 137-43, 1983.
Article
en En
| MEDLINE
| ID: mdl-6573735
ABSTRACT
Rats fed either a low (2p. 100) or high (40 p. 100)-fat diet were exposed to 22 or 5 degrees C. The resulting hyperphagia adequately compensated energy losses as judged from body weight. The cold-induced hyperphagia was accompanied by a non-parallel increase in pancreatic hydrolases. Amylase and lipase were not increased above the adaptive levels they had respectively reached in the heat with a high-starch or high-lipid diet. Chymotrypsinogen, on the contrary, responded to increased intake of both diets. It also responded to the higher protein concentration in the high-fat diet caused by isocaloric replacement of starch by fat. Colipase varied independently of lipase and was increased additively by fat and protein intakes. Consequently, although limiting for lipase in the warm, colipase rose to a 11 ratio in the cold. Increased intake had a consistent pleiotropic effect evidenced by an increase of amylase with the high-fat diet and of lipase with the low-fat diet. The net effect was a significant increase in the lipid-digesting potential of the organism of lipid-fed animals upon exposure to cold, while the starch-digesting potential remained unaffected in starch-fed animals.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Páncreas
/
Grasas de la Dieta
/
Hiperfagia
/
Trastornos de Alimentación y de la Ingestión de Alimentos
/
Frío
/
Hidrolasas
Tipo de estudio:
Etiology_studies
Límite:
Animals
/
Humans
/
Male
Idioma:
En
Revista:
Reprod Nutr Dev (1980)
Año:
1983
Tipo del documento:
Article