Lack of an elevated risk of malignant melanoma in relation to oral contraceptive use.
J Natl Cancer Inst
; 72(3): 617-20, 1984 Mar.
Article
en En
| MEDLINE
| ID: mdl-6583445
ABSTRACT
Epidemiologic and laboratory data suggest an effect of oral contraceptives (OC) on the risk of malignant melanoma. This relationship was explored in a hospital-based case-control study of 160 women with malignant melanoma and 640 matched controls, all of whom were white and 20-59 years of age. A total of 63 cases (39%) had used OC compared with 270 controls (42%), yielding a relative risk estimate of 0.9 (95% confidence interval 0.6-1.3). When a number of potential confounding factors were simultaneously controlled, the relative risk estimate was 0.8 (0.5-1.3). For use that lasted 5 or more years the estimate was 0.9 (0.5-1.6). The level of tumor invasion was not related to OC use. The evidence from this study suggests that OC, even when used for 5 or more years, do not increase the risk of malignant melanoma.
Palabras clave
Biology; Cancer; Contraception; Contraception Continuation; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Methods--side effects; Data Analysis; Data Collection; Dermatological Effects--changes; Diseases; Family Planning; Neoplasms; Oral Contraceptives--side effects; Physiology; Population At Risk; Reproductive Control Agents; Research Methodology
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Anticonceptivos Orales
/
Melanoma
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Female
/
Humans
País/Región como asunto:
America do norte
Idioma:
En
Revista:
J Natl Cancer Inst
Año:
1984
Tipo del documento:
Article