Presence of immunoreactive corticotropin-releasing factor in human cerebrospinal fluid.
J Clin Endocrinol Metab
; 57(1): 225-6, 1983 Jul.
Article
en En
| MEDLINE
| ID: mdl-6602142
ABSTRACT
Immunoreactive corticotropin-releasing factor (I-CRF) was measured by radioimmunoassay and immunoaffinity chromatography in human hypothalamus and cerebrospinal fluid (CSF). Dilution curves of I-CRF in the hypothalamus and CSF were parallel to that of synthetic ovine CRF standard. I-CRF content in the hypothalamus was 643 and 281 fmol eq, respectively. I-CRF concentration in CSF was 7.4 +/- 1.1 fmol eq/ml. Sephadex G-75 column chromatography showed the main peak eluted at the position of synthetic CRF.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hormona Liberadora de Corticotropina
/
Hipotálamo
Límite:
Humans
Idioma:
En
Revista:
J Clin Endocrinol Metab
Año:
1983
Tipo del documento:
Article